WIAS Preprint No. 1578, (2010)

Image analysis and statistical inference in neuroimaging with R


  • Tabelow, Karsten
    ORCID: 0000-0003-1274-9951
  • Clayden, Jon D.
  • Lafaye de Micheaux, Pierre
  • Polzehl, Jörg
    ORCID: 0000-0001-7471-2658
  • Schmid, Volker J.
  • Whitcher, Brandon

2010 Mathematics Subject Classification

  • 62P10 92C55 62H35 62G05


  • diffusion weighted imaging, functional magnetic resonance imaging, dynamic contrast-enhanced magnetic resonance imaging, computational neuroscience




R is a language and environment for statistical computing and graphics. It can be considered an alternative implementation of the S language developed in the 1970s and 1980s for data analysis and graphics (Becker and Chambers, 1984; Becker et al., 1988). The R language is part of the GNU project and offers versions that compile and run on almost every major operating system currently available. We highlight several R packages built specifically for the analysis of neuroimaging data in the context of functional MRI, diffusion tensor imaging, and dynamic contrast-enhanced MRI. We review their methodology and give an overview of their capabilities for neuroimaging. In addition we summarize some of the current activities in the area of neuroimaging software development in R.

Appeared in

  • NeuroImage, 55 (2011) pp. 1686--1693

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