To the website of the group of PhD students at the Weierstrass-Institute for Applied Analysis and Stochastics!
|12.12.2022||Christine Keller (RG 7) |
Development of an Ion-Channel Model-Framework
Ion channels are pore-forming proteins in the cell membrane that control a large part of biological processes, e.g., the generation of electrical signals in the nervous and muscle systems. The behavior of ion channels can be studied in the laboratory by measuring the current response to a time-dependent voltage difference. This signal is a unique signature of each channel and its environment, as it varies with the structure of the channel protein and the ion concentration. Its interpretation is therefore of great interest for the development of medications and therapies in medicine. The development of a model-framework can support the interpretation of this current-voltage relation and contribute to a better understanding. In this talk, a model will be presented that describes ion activities in the channel using non-equilibrium thermodynamics and mixing theories. The model accounts for size and correlation phenomena such as space charge competitions and finite volume effects, as well as solvation effects of ions in aqueous electrolytes.
This month's speaker: Jun. Prof. Dr. Hanna Drimalla, who is Junior-Professor at the Technical Faculty of Bielefeld University and leads the Multimodal Behavior Processing research group. Her work focuses on automatic affect recognition, computer-based stress measurement, and analysis of social embedding. In her talk, she will tell us about her personal journey in academia (including some detours) and the ups and downs of an interdisciplinary career between psychology and computer science.
Location & Time: Wednesday, 2022-11-30, 17:00-18:30, Zoom
You can register here to receive the Zoom invite link.
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